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Christina Applegate’s Representatives responded to reports that the actress was hospitalized due to her battle with multiple sclerosis.
TMZ report Thursday, April 16, Married…with children The 54-year-old alum was admitted to the hospital in late March and is currently hospitalized in a Los Angeles hospital. It’s unclear whether her hospitalization was due to multiple sclerosis.
Applegate representatives told US Weekly In a statement, “I have no comment on whether she was in the hospital or the treatment she received. She has long suffered from complex medical conditions, about which she has been refreshingly open, as evidenced in her memoir and podcast.”
Applegate once said candidly Her battle with multiple sclerosis (MS) since she publicly revealed her diagnosis in August 2021.
“It’s been a weird journey,” she wrote via X at the time. “But I’ve had a lot of support from people I know who have this disease. It’s a tough road. But as we all know, it’s going to be a long road. Unless some asshole gets in the way of it.”
talking type In November 2022, Applegate recalled experiencing symptoms while filming Netflix’s “Dead to Me.”
“I didn’t know what was happening to me. In January of that year, my toes went numb and I ignored it. The ball of my foot went numb and I ignored it. All of a sudden, it was like I fell,” she explained. “People were like, ‘Oh, it’s just psycho.’ At this point, they had to take me to the set in a wheelchair because I couldn’t walk far away from the set. I was sleeping all the time, gained 40 pounds—a lot was going on.”

Christina Applegate.
(Photo: Axelle/Bauer-Griffin/FilmMagic)January 2026 She details a recent outburst and expressed concern that multiple sclerosis might “take” her away.
Applegate got emotional during an appearance on the “MeSsy” podcast, which she co-hosts with Jamie-Lynn Siegler.
In an emotional moment, Applegate read a letter from a fan named Steven, who has myasthenia gravis (MG). Autoimmune diseases can cause weakness in certain voluntary muscles. Steven wrote that MG “snatched (his) soul day after day, hour after hour,” reminding Applegate of his recent multiple sclerosis outbreak.
“I was reading the book and I was trying not to become a crybaby again because of everything I read because I was getting so emotional because we were all sitting in that space and I was really moved,” she said. “Like yesterday, I was walking, okay… Today, I fell, I tripped. I just feel like, is it taking me away? Is it taking me away, day by day, bit by bit? I can’t even read something like this without being super hyper-triggered.”
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