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Eric Dane died on the 20th anniversary of his debut Grey’s Anatomy.
Dane’s relatives confirmed his death in a statement On Thursday, February 19, after battling ALS, he noted that the actor “spent his final days surrounded by his dear friends, his devoted wife, and his two beautiful daughters, Billie and Georgia, who were the center of his world.”
The same day also marks the 20th anniversary of his departure. Debuts on ABC TV Grey’s Anatomy. Dane debuted as Dr. Mark Sloane in the Season 2 episode 18, “Yesterday”, which aired on February 19, 2006.
“Mark Sloan (McStimi) arrives at Seattle Grace, forcing Derek and Addison to confront their past,” the episode’s synopsis read at the time.
One season later, Dane returns and takes on a larger role Remained on the show until 2012. His character eventually died from injuries sustained in a plane crash.
“I thought I was fired,” Dane said in a 2024 episode of The Armada, recalling her exit from the show.
Dane also opened up about battling drug addiction after entering a treatment center in 2011. He insists the purpose of the show is The producers “didn’t let me go because of that.”
“It certainly didn’t help though. I started to become – like most actors who spend a lot of time on a show, you start to become very expensive to the network,” he explained. “The network knows that no matter who they keep, the show is going to do what it wants to do. As long as they still have ‘The Gray Robes,’ they’ll be fine.”

He concluded: “I wasn’t the person they hired. So when I got fired, I understood. And (executive producer) Shonda (Rimes) was really great. She was fiercely protective of us. She was protective of us publicly. She was protective of us privately…but I might have been fired. It wasn’t like, ‘You’re fired,’ it was, ‘You’re not coming back.'”
Dane finally wakes up Continue booking roles In such cases as Euphoria and Countdown. In April 2025, shortly before Euphoria was set to begin filming its third and final season, he announced his battle with ALS.
Before his death, Dane opened up about his diagnosis and worked with organizations like I AM ALS to raise awareness. I AM ALS honored him in a heartfelt statement Thursday.
“We are heartbroken by the passing of our friend Eric Dane, a fierce advocate with a generous spirit and a true champion of the movement to end ALS. Eric used his platform not to draw attention but to take action,” their message states. “From the moment he joined I AM ALS, he showed up with the courage and conviction to ask how he could use his superpowers to help the movement grow. I was honored to brainstorm with him and walk the halls of Congress with him on behalf of our community to amplify the critical need for ALS and research funding for ACT and to advance treatments and ultimately a cure. He understands that ALS is more than a diagnosis; it is a call to families, answers, and change.”
The organization promises Continuing Dane’s legacy.
“Eric brought humility, humor, and visibility to ALS and reminded the world that progress is possible when we refuse to remain silent,” their statement continued. “Eric was more than just a supporter of our mission, he was a member of our family. His impact will live on in the research he funded, the policies he advanced and the communities he helped grow through his honesty, bravery and his belief in a better future for anyone battling this diagnosis.”
The statement concluded: “We honor Eric by continuing the work he deeply believed in: mobilizing communities, advancing critical research, securing necessary funding, and fighting tirelessly for real solutions. Our hearts go out to his loved ones and the entire community. I Am ALS will carry on his legacy—until ALS is no more.”